1) Collar way too tight
2) Large squamous cell carcinoma under tongue
3) Ants invading the cat food bowl
4) 1 1/2" skull tumor keeping it from being able to open its mouth
5) Stomach completely packed full of cat fur
6) Unregulated diabetes
7) 16 rotten, loose teeth
8) Uncontrolled hyperthyroidism
9) Complete bone marrow shutdown of unknown cause
10)Rubber band around base of tail causing the whole thing to die
There are more, of course. These are just some of the causes for weight loss I have seen in my years in practice.