AVMA has a new podcast that may be of help to multicat owners who are seeing aggression issues between their cats. The main aggression problems we see in housecats are territorial aggression and redirected aggression. Pain can also cause aggression, so it's best to get kitty in for an exam and consultation about the problem so we can be sure what type of aggression we are dealing. Only then can we make appropriate management recommendations.
Early warning signs of aggression are holding ears back, tail twitching, or growling/hissing. Never attempt to handle a cat which is acting aggressively, particularly if it is reacting to another cat that it can't get to - it will attack whoever is convenient and that may just be YOU!